On Sunday morning, a drone strike killed four suspected militants in Miramshah, the capital of North Waziristan.
The identities of those killed in the two attacks have not yet been ascertained, an intelligence official, wishing not to be named, told Anadolu Agency.
Addressing the UN General Assembly in New York on Friday, Prime Minister Nawaz Sharif blasted the drone attacks as a violation of Pakistan's sovereignty.
"The attacks conducted by US-led NATO forces on Pakistani soil using unmanned spy planes are counter-productive to the anti-extremism efforts," he insisted.
"It results in casualties of innocent civilians and is detrimental to our resolve and efforts to eliminate extremism and terrorism from Pakistan," he added.
North Waziristan, seen as the headquarters of the formidable Haqqani network, has been the prime target of US drone attacks for the last five years.
More than 3,000 people, including women and children, have been killed in drone attacks in the region since 2004.
According to Washington-based think tank the New American Foundation, Some 116 Al-Qaeda and Taliban fighters have also been killed in drone attacks.
The US describes unmanned aerial drone strikes as one of its most precise and useful weapons against Al-Qaeda and Taliban militants holed up in Waziristan.
In contrast, human rights organizations and independent think tanks, like the New American Foundation and the Bureau of Investigative Journalism, say that 70 percent of those killed in drone attacks have been civilians.